英文名稱 | Deruxtecan | DS-8201a | exatecan derivative | DX 8951; |
---|---|
中文名稱 | 德魯替康 |
CAS號 | 1599440-13-7 |
分子式 | C52H56FN9O13 |
分子量 | 1,034.05 |
外觀 | White to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Deruxtecan | DS-8201a | exatecan derivative | DX 8951; |
---|---|
中文名稱 | 德魯替康 |
CAS號 | 1599440-13-7 |
分子式 | C52H56FN9O13 |
分子量 | 1,034.05 |
外觀 | White to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan (DX-8951).