英文名稱(chēng) | Poseltinib | HM71224 | LY3337641 |
---|---|
中文名稱(chēng) | 波塞替尼 | HM71224 | LY3337641 | 酪氨酸蛋白激酶 BTK 抑制劑 |
CAS號(hào) | 1353552-97-2 |
分子式 | C26H26N6O3 |
分子量 | 470.52 |
外觀 | Light yellow to yellow powder |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專(zhuān)享價(jià) | 數(shù)量 |
---|---|---|---|---|
1 mg | 3-5days | ¥898.00 | 登錄后可見(jiàn) | |
5 mg | 3-5days | ¥1868.00 | 登錄后可見(jiàn) |
英文名稱(chēng) | Poseltinib | HM71224 | LY3337641 |
---|---|
中文名稱(chēng) | 波塞替尼 | HM71224 | LY3337641 | 酪氨酸蛋白激酶 BTK 抑制劑 |
CAS號(hào) | 1353552-97-2 |
分子式 | C26H26N6O3 |
分子量 | 470.52 |
外觀 | Light yellow to yellow powder |
Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor. With an IC50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis.