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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
1 mg	In-stock	￥436.00	登錄后可見(jiàn)	- +
5 mg	In-stock	￥1066.00	登錄后可見(jiàn)	- +
10 mg	In-stock	￥1918.00	登錄后可見(jiàn)	- +
25 mg	In-stock	￥3366.00	登錄后可見(jiàn)	- +
50 mg	In-stock	￥5016.00	登錄后可見(jiàn)	- +
100 mg	In-stock	￥7016.00	登錄后可見(jiàn)	- +
250 mg	In-stock	￥9026.00	登錄后可見(jiàn)	- +
500 mg	In-stock	￥13660.00	登錄后可見(jiàn)	- +
1 g	In-stock	￥21068.00	登錄后可見(jiàn)	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

1 mg

In-stock

￥436.00

登錄后可見(jiàn)

- +

5 mg

In-stock

￥1066.00

登錄后可見(jiàn)

- +

10 mg

In-stock

￥1918.00

登錄后可見(jiàn)

- +

25 mg

In-stock

￥3366.00

登錄后可見(jiàn)

- +

50 mg

In-stock

￥5016.00

登錄后可見(jiàn)

- +

100 mg

In-stock

￥7016.00

登錄后可見(jiàn)

- +

250 mg

In-stock

￥9026.00

登錄后可見(jiàn)

- +

500 mg

In-stock

￥13660.00

登錄后可見(jiàn)

- +

1 g

In-stock

￥21068.00

登錄后可見(jiàn)

- +

基本信息

英文名稱	Deucravacitinib (Synonyms: BMS-986165；氘可來(lái)昔替尼 ; 德克拉維替尼 ; BMS-986165 ; 酪氨酸蛋白激酶 TYK2 負(fù)異位調(diào)節(jié)劑)
中文名稱	6-(環(huán)丙烷甲酰胺基)-4-((2-甲氧基-3-(1-甲基-1H-1,2,4-三唑-3-基)苯基)氨基)-N-(甲基-D3)噠嗪-3-甲酰胺
CAS號(hào)	1609392-27-9
分子式	C20H19D3N8O3
分子量	425.46
MDL	MFCD31715455
外觀	Off-white to light yellow powder
儲(chǔ)存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

產(chǎn)品詳情

Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain.

相關(guān)文獻(xiàn)

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.

PMID: 31318208 DOI: 10.1021/acs.jmedchem.9b00444

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CL2962

6-(環(huán)丙烷甲酰胺基)-4-((2-甲氧基-3-(1-甲基-1H-1,2,4-三唑-3-基)苯基)氨基)-N-(甲基-D3)噠嗪-3-甲酰胺

1609392-27-9 Purity: 99.73% In-stock

￥436.00 1 mg