英文名稱 | Flavopiridol | Alvocidib | NSC 649890 | HMR-1275 | L86-8275 |
---|---|
中文名稱 | 夫拉平度 |
CAS號 | 146426-40-6 |
分子式 | C21H20ClNO5 |
分子量 | 401.84 |
外觀 | Light yellow to yellow powder |
儲存條件 | 4°C, stored under nitrogen |
英文名稱 | Flavopiridol | Alvocidib | NSC 649890 | HMR-1275 | L86-8275 |
---|---|
中文名稱 | 夫拉平度 |
CAS號 | 146426-40-6 |
分子式 | C21H20ClNO5 |
分子量 | 401.84 |
外觀 | Light yellow to yellow powder |
儲存條件 | 4°C, stored under nitrogen |
Potent inhibitor of cyclin-dependent kinases (CDKs). Induces apoptosis in certain tumor cells. Interacts with multidrug resistance protein 1 (MRP1)
PMID: 31349793 PMCID: PMC6660968 DOI: 10.1186/s12964-019-0398-3
PMID: 22740450 PMCID: PMC3418721 DOI: 10.1182/blood-2011-12-400184
Complex effects of flavopiridol on the expression of primary response genes.
PMID: 11063609 DOI: 10.1021/jm000231g