英文名稱 | SB-505124 hydrochloride |
---|---|
中文名稱 | SB-505124 HCl |
CAS號 | 356559-13-2 |
分子式 | C20H22ClN3O2 |
分子量 | 371.86 |
外觀 | Light yellow to green yellow powder |
儲存條件 | 4°C, sealed storage, away from moisture |
英文名稱 | SB-505124 hydrochloride |
---|---|
中文名稱 | SB-505124 HCl |
CAS號 | 356559-13-2 |
分子式 | C20H22ClN3O2 |
分子量 | 371.86 |
外觀 | Light yellow to green yellow powder |
儲存條件 | 4°C, sealed storage, away from moisture |
SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
PMID: 14978253 DOI: 10.1124/mol.65.3.744
PMID: 21031133 PMCID: PMC2956700