英文名稱 | GSK583 |
---|---|
中文名稱 | GSK583 |
CAS號(hào) | 1346547-00-9 |
分子式 | C20H19FN4O2S |
分子量 | 398.45 |
外觀 | Light yellow to yellow powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
規(guī)格 | 庫存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 | |
---|---|---|---|---|---|
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英文名稱 | GSK583 |
---|---|
中文名稱 | GSK583 |
CAS號(hào) | 1346547-00-9 |
分子式 | C20H19FN4O2S |
分子量 | 398.45 |
外觀 | Light yellow to yellow powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
GSK583 is a highly potent and selective inhibitor of RIP2 kinase with IC50 of 5 nM. GSK583 also inhibits both TNF-α and IL-6 production with IC50 of ~200 nM in explant cultures.