英文名稱 | Combretastatin A4 Disodium Phosphate(CA4P) |
---|---|
中文名稱 | 康普瑞汀磷酸二鈉 |
CAS號(hào) | 168555-66-6 |
分子式 | C18H19PO8Na2 |
分子量 | 440.29 |
外觀 | white powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 |
---|---|---|---|---|
10 mg | In-stock | ¥700.00 | 登錄后可見(jiàn) | |
20 mg | In-stock | ¥1120.00 | 登錄后可見(jiàn) | |
50 mg | In-stock | ¥2200.00 | 登錄后可見(jiàn) |
英文名稱 | Combretastatin A4 Disodium Phosphate(CA4P) |
---|---|
中文名稱 | 康普瑞汀磷酸二鈉 |
CAS號(hào) | 168555-66-6 |
分子式 | C18H19PO8Na2 |
分子量 | 440.29 |
外觀 | white powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Fosbretabulin (Combretastatin A4 Phosphate, CA4P, CA 4DP) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Fosbretabulin disodium induces mitotic arrest and apoptosis in endothelial cells. Phase 3.