英文名稱 | Ramatroban |
---|---|
中文名稱 | 雷馬曲班 |
CAS號 | 116649-85-5 |
分子式 | C21H21FN2O4S |
分子量 | 416.47 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Ramatroban |
---|---|
中文名稱 | 雷馬曲班 |
CAS號 | 116649-85-5 |
分子式 | C21H21FN2O4S |
分子量 | 416.47 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Ramatroban is a novel, potent and selective antagonist of thromboxane A2 (TxA2) with an IC50 of 14 nM. It also inhibits PGD2 binding, which antagonizes CRTH2 (IC50=113 nM). In addition to treating asthma, ramatroban is recommended for the treatment of coronary artery disease.