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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
5 g	3-5days	￥200.00	登錄后可見	- +
10 g	3-5days	￥300.00	登錄后可見	- +
25 g	3-5days	￥500.00	登錄后可見	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

5 g

3-5days

￥200.00

登錄后可見

- +

10 g

3-5days

￥300.00

登錄后可見

- +

25 g

3-5days

￥500.00

登錄后可見

- +

基本信息

英文名稱	Orlistat (Synonyms: Tetrahydrolipstatin; Ro-18-0647)
中文名稱	奧利司他
CAS號(hào)	96829-58-2
分子式	C29H53NO5
分子量	495.73
外觀	White to off-white powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Orlistat (also known as tetrahydrolipstatin, or Ro 18-0647, Lipase Inhibitor, THL ) is a potent and general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice. Orlistat is a drug designed to treat obesity. Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. Mechanistic studies suggest that Orlistat inhibits the thioesterase domain of fatty acid synthase (FAS) and as a result halts cell proliferation and causes cell apoptosis. More detailed experiments show that gradually Orlistat affects the retinoblastoma protein pathway and leads to cell-cycle arrest at G1/S boundary.

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瀏覽記錄

CL2557

奧利司他

96829-58-2 98+% 3-5days

￥200.00 5 g

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奧利司他

Orlistat (Synonyms: Tetrahydrolipstatin; Ro-18-0647)

化學(xué)品安全說(shuō)明書(MSDS)