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規(guī)格	庫存	目錄價(jià)	會員專享價(jià)	數(shù)量
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規(guī)格

庫存

目錄價(jià)

會員專享價(jià)

數(shù)量

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基本信息

英文名稱	Capecitabine \| RO 09-1978 \| Xeloda
中文名稱	卡培他濱
CAS號	154361-50-9
分子式	C15H22FN3O6
分子量	359.35
外觀	White to off-white powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

相關(guān)文獻(xiàn)

Capecitabine: A review.

https://doi.org/10.1016/j.clinthera.2005.01.005

PMID: 18077151 DOI: 10.1016/j.ejca.2007.10.023

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卡培他濱

Capecitabine | RO 09-1978 | Xeloda

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