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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
2 mg	3-5days	￥866.00	登錄后可見	- +
5 mg	3-5days	￥1068.00	登錄后可見	- +

基本信息

英文名稱	SKLB4771 \| FLT3-IN-1
中文名稱	SKLB4771 \| FLT3-IN-1
CAS號	1370256-78-2
分子式	C25H27N7O3S2
分子量	537.66
外觀	Light yellow to yellow powder
儲存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

產品詳情

SKLB4771 is a potent and selective Flt3 inhibitor with an IC₅₀ value of 10 nM. SKLB4771 downregulates the phosphorylation of FLT3/STAT5/ERK, blocks cell proliferation, and induces apoptosis in tumor tissue.

相關文獻

Accumulation of FLT3(+) CD11c (+) dendritic cells in psoriatic lesions and the anti-psoriatic effect of a selective FLT3 inhibitor.

PMID: 24895100 DOI: 10.1007/s12026-014-8521-4

Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo.

PMID: 22452518 DOI: 10.1021/jm300042x

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瀏覽記錄

CL2954

SKLB4771 | FLT3-IN-1

1370256-78-2 98+% 3-5days

￥866.00 2 mg

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SKLB4771 | FLT3-IN-1

SKLB4771 | FLT3-IN-1

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