英文名稱 | Denosumab (anti-RANK ligand) | AMG-162 |
---|---|
中文名稱 | 地諾單抗 | 狄諾塞麥 | 地舒單抗 |
CAS號 | 615258-40-7 |
儲存條件 | Sealed and stored at ≤-30℃, away from light. Avoid freeze-thaw cycles |
英文名稱 | Denosumab (anti-RANK ligand) | AMG-162 |
---|---|
中文名稱 | 地諾單抗 | 狄諾塞麥 | 地舒單抗 |
CAS號 | 615258-40-7 |
儲存條件 | Sealed and stored at ≤-30℃, away from light. Avoid freeze-thaw cycles |
Denosumab (anti-RANK ligand) (AMG-162, Prolia, Xgeva) is a fully human monoclonal antibody that selectively inhibits primate RANKL. Denosumab inhibits the ability of human RANKL (143–317) to stimulate the formation of osteoclasts derived from murine RAW 264.7 cells with an IC50 value of 1.64 nM.