英文名稱 | Virgaureagenin G | Polygalacic acid |
---|---|
中文名稱 | 毛果一枝黃花皂苷元G | 遠志酸 |
CAS號 | 22338-71-2 |
分子式 | C30H48O6 |
分子量 | 504.71 |
外觀 | White to off-white powder |
儲存條件 | 4°C, protect from light |
英文名稱 | Virgaureagenin G | Polygalacic acid |
---|---|
中文名稱 | 毛果一枝黃花皂苷元G | 遠志酸 |
CAS號 | 22338-71-2 |
分子式 | C30H48O6 |
分子量 | 504.71 |
外觀 | White to off-white powder |
儲存條件 | 4°C, protect from light |
Polygalacic acid (Virgaureagenin G) is a triterpenoid isolated from the root of Polygala tenuifolia Willd that inhibits MMP expression. Polygalacic acid (Virgaureagenin G) can significantly improve the responsiveness of the cholinergic system, such as decreased acetylcholinesterase (AChE) activity, increased choline acetyltransferase (ChAT) activity, and increased acetylcholine (ACh) levels in the hippocampus and frontal cortex. Polygalacic acid (Virgaureagenin G) can also inhibit IL-1β-induced Wnt/β-catenin activation and mitogen-activated protein kinase (MAPK) signaling pathways in chondrocytes, and is used in osteoarthritis (OA) related research.
PMID: 20939516 DOI: 10.1021/np100496p
Neuroprotective effects of polygalacic acid on scopolamine-induced memory deficits in mice.
PMID: 26926176 DOI: 10.1016/j.phymed.2015.12.009
PMID: 38421141 PMCID: PMC10851321 DOI: 10.1111/cns.14581
PMID: 30119032 DOI: 10.1016/j.intimp.2018.08.013